Based on severity in two categories: macromastia and gigantomastia. The disease is usually due to increased sensitivity of mammary gland tissue to female sex hormones, prolactin, and growth factors. Breast hypertrophy is a benign progressive disease, which can occur in both breasts or on only one breast, usually on both sides of the breast. Breast enlargement was first described in 1648. Until now, there have been no large reports of this disease in the world and in the country. There are a few cases reported by Military Hospital 108 and Hospital K. At Phu Tho General Hospital this is the first case of the disease was discovered and treated.
At present, there is no uniform definition of breast hypertrophy, which is the most widely accepted definition: It is called breast hypertrophy when the breast mass exceeds 3% of body mass. There are different types of classification depending on the circumstances. Sort by level: Breast hypertrophy (macromastia) when mass <2.5 kg; Giant mammal (gigantomastia) when mass> 2.5kg. Age classification includes vaginal hypertrophy (puberty), breast enlargement during pregnancy (occurring during or after pregnancy), breast enlargement (infants under 2 years of age) ).
Breast Enhancement Breast Enhancement (12 year old female)
Hypertrophy of pregnancy (24 years of age, 28 weeks gestation)
Breast enlargement of infants (6 months old)
Reason
The cause of breast enlargement to this point is not clear, but there are some assumptions:
- Due to increased levels or increased sensitivity to some sex hormones: estrogen, progesterone, prolactin
- Due to some growth factors: GH, Insulin, EGF ...
In which large breast (macromastia) usually only increases the tissue buffer, fat in the chest, breast tissue of the mammary gland. Giant mammary gland (gigantomastia), which is actually a mammary gland, is often associated with metabolic and genitourinary disorders.
Treatment for breast enlargement:
Because the cause of this disease is unknown, so far there is no effective treatment methods, the main treatment interfere with the mechanism of the effect of sex hormones, growth or surgical intervention. To create or cut off the breast development is excessive, causing serious consequences for patients.
- Internal medicine can use female hormone antagonists such as tamoxifen, testosterol, Gonadotropin analogs, dopamine agonist.
Surgery is usually indicated if the medical treatment fails or if the mammary gland develops at a level that affects the overall condition or causes nerve or necrotizing breast tissue. Commonly used techniques include breast reconstruction surgery, mastectomy surgery for giant breast cases.
A rare case of breast hypertrophy was successfully treated at the Center for Oncology
A case of breast appearance to the public is very interested in the last time. Dinh Thi L, 31, from the Muong ethnic group, lives in Tan Son district, Phu Tho province. The history of the body and maternity of the patient is not very special: First menstrual period of 17 years, the cycle is regular. Getting married at the age of 22, giving birth to a baby at 23 years of age, giving birth, breastfeeding, then the breast of the patient grows normally. The family is healthy, no one has any special health problems.
The second child is 30 years old. At 3 months of pregnancy, 2 breast growth abnormally fast, prolonged flow to the navel. Second birth in Phu Tho province, birth two, breast continued to grow to the inguinal level. Postmenopausal MRI scans do not show abnormalities, genital hormone tests are suitable for pregnancy status. After birth 2 breast continued to grow, a lot of milk, afraid patients do not dare to breastfeed. After mid-February, the breasts grow to the thigh. Patient hospitalized 23/2/2016 at Surgery - Oncology Unit, in the status of the province, normal survival indicators, weight 65kg. Patients suffering severe pain due to two large breast size, more milk; The left armpit has an extra mammary gland, the armpit must have two extra mammary glands, the size of the secondary mammary gland is about 15cm. Experts: HH, SHM, Sex hormone, armor within normal limits, Prolactin 2680 Micro U / ml (Normal for pregnant and lactating women). MRI cerebral cortex with no evidence of brain and pituitary abnormalities. Patients are diagnosed with mammary gland enlargement during pregnancy. After consultation with TTUB, MD, MD, MD, MD, Department of Endocrinology, Internal Medicine, in combination with internal medicine, control lactation, PT will remove 2 breast and mammary glands. extra. Internal Medicine: Dostinex 0.5mg x 1 tablet / week (Cabergoline - Dopamine D2 agonist suppresses Prolactin secretion from the pituitary, hypothalamic). After a week of taking the drug, Prolactin tested to 30Micro U / ml; 2 breasts stopped lactation, weighed down 5kg patients. Decision of surgical intervention to remove 2 breasts and extra breast lines on day with the support of National Center K specialist. The specimen weighs 10kg. Surgery after surgery: benign mammary epithelial epithelium. After surgery, the patient continues to maintain drug Dostinex. Breast implant surgery is scheduled for 2 months, however, during a routine follow-up period, the patient refuses to undergo breast implant surgery due to lack of condition.
Some pictures of patients before and after treatment: Pre-treatment patients with two large mammary glands extra mammary glands
pictures before surgery
Patients after surgery 5 days
